Selma Blair reflects on a 2016 incident where she mixed prescription drugs with alcohol on a flight, leading to a scary outburst and hospitalization. This event marked her lowest point with alcohol, prompting her to embrace sobriety and eventually receive a multiple sclerosis (MS) diagnosis. Blair acknowledges that being sober was crucial for her MS diagnosis and parenting. The actress highlights the importance of sobriety in her journey, noting that it enabled her to address her health issues and be a better mother. Blair's openness about her struggles with alcohol and subsequent sobriety has been a significant part of her personal growth and health journey.