The New England Patriots lost 27-21 to the Buffalo Bills in a game that saw the Patriots struggle with early turnovers, including a 98-yard kickoff return by Jalen Reagor and a pick-six to Rasul Douglas. The Bills capitalized on these mistakes and scored 20 unanswered points in the second quarter, taking a commanding lead. Despite a strong defense and a late touchdown pass from Bailey Zappe, the Patriots could not overcome the deficit. The loss drops the Patriots to a 4-12 record and their next game will be against the New York Jets. The Bills, with this win, maintain their position as the top seed in the AFC playoff picture and are set to play against the Miami Dolphins in Week 18.