The Buffalo Bills are facing significant challenges as they head into their preseason finale, primarily due to a slew of injuries affecting key players. Head coach Sean McDermott announced that starters, including quarterback Josh Allen, will be held out of the upcoming game against the Carolina Panthers to evaluate other roster options, given that 14 players are currently injured. Notable absences include linebacker Matt Milano, who faces an indefinite recovery after a biceps tear, and quarterback Mitch Trubisky, who will miss several weeks. McDermott expressed both concern and optimism regarding the offense, which has yet to score a touchdown in the preseason, citing issues with execution and offensive line performance. As the team struggles to find its rhythm, the coaching staff is exploring potential quarterback options to address the thin roster. With the season approaching, the Bills’ injury situation remains critical and will influence their performance moving forward.