In a stunning upset at the US Open 2024, Alexei Popyrin defeated World No. 2 Novak Djokovic in the third round, with a score of 6-4, 6-4, 2-6, 6-4. This victory marks a significant milestone for Popyrin, who has struggled with injuries throughout his career and had previously lost to Djokovic twice this year. Djokovic's defeat means he finishes the year without a Grand Slam title for the first time since 2017, as well as marking the first time since 2002 that none of the 'Big Three' have won a Slam. The match demonstrated Popyrin's resilience as he maintained control in the fourth set despite Djokovic's attempts to rally. Popyrin will now face the winner of the match between Ben Shelton and Frances Tiafoe in the next round.